Objective: Sepsis is a common disease in internal medicine, with a high incidence and dangerous condition.Due to the limited understanding of its pathogenesis, the prognosis is poor.The goal of this project is to screen potential biomarkers for the diagnosis of sepsis and to identify competitive endogenous RNA (ceRNA) networks associated with sepsi
Malaria transmission risk is projected to increase in the highlands of Western and Northern Rwanda
Abstract Malaria is one of the major health threats in Africa, and the risk of transmission is projected to be exacerbated by global warming.Rwanda experienced an 11-fold increase in malaria incidence from 2011 to 2015 despite extensive funding and implementation of control measures.Here, we focus on Rwanda as a case study and simulate Ball - Glove
Methanethiol: A Scent Mark of Dysregulated Sulfur Metabolism in Cancer
In order to cope with increased demands for energy and metabolites as well as to enhance stress resilience, tumor cells develop various metabolic adaptations, representing a hallmark of cancer.In this regard, the dysregulation of sulfur metabolism that may result in Chaise elevated levels of volatile sulfur compounds (VSCs) in body fluids, breath,
Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing
Abstract Background RNA interference (RNAi) was originally identified as a biological process in which short double-stranded RNA (dsRNA) suppress the expression of genes complimentary to Butterbur the dsRNA.This cellular intrinsic gene silencing mechanism has subsequently been developed as a useful tool for studies of gene function.A major strategy